How can I talk my wife out of her depression?

She has been a negative nancy for the past 3 months... She cries basically all day, lays in bed, and even soils herself as to not not get up to go to the bathroom. We've not made love in a year, our entire family is worried and i'm about to bail on her. I won't allow her to take mood altering medications because i gurantee that is a ploy by the right wing republicans to keep America stupid. That's neither here nor there though. I need some good talk therapy words to say to her to get her feeling better and moving on with our life.